[sunmukh_singh]

hello ,
i have a pug who is 1 year old and is suffering from canine distemper virus. i have consulted many vet doctors but i couldnt find any cure for him . i am very worried about him as his condition is getting worst day after day ........
i will really appretiate if u could help me out... my e mail id is [moderator note: e-mail address has been removed] .....
i will be waiting for your reply desperately.......
thank you ..

[Daveyo]

Is your e-mail correct?? Respond quick.

[maiziedog]

Help. I am desperate. We just got a new puppy(7-8mos?) for Christmas. She developed a cough, then pnuemonia and was completely lethargic - didn't eat for almost 4-5days. Her temp was usually around 103.5 On the penecillin and then finally Baytril, she beat the respiratory stuff and had begun to want to play again. She never had the diahrea and only vomited after being given Keflex. Now she's progressed into the twitching, can hardly keep her leg still at times. She's definitely weak and has a hard time having the mind/body coordination to do things such as climb stairs. She can't figure out how to even jump up on the bed. (The first day we had her, she jumped all the way on top of the table while we were eating!) She picked my daughter out when we went to the shelter to see the puppies and is the sweetest dog I've ever met. She just has these eyes that are telling me "do something!" But I don't know what to do. I see here that someone's talking about a distemper cure. Could you let me know what to do and if it's too late once she's reached the neurological stage of distemper? I'm at a loss. We've already spent lots of money, and don't mind spending a little more if necessary. I just don't want to see her suffer along with my 4 year old daughter who got her as a Christmas present from my husband and me.

[Daveyo]

Hi I am Daveyo

What is happening right now with your dog is the T-4 killer cells are destroying the myelin inside the spinal cord CNS system. Under normal circumstances this is PARALYSIS ONCOMING, and it progresses leading to being fatal. Dogs will expire without getting the NDV.

However, you can stop this PROGRESSION and the dog will live. You have to do the NDV-CSF tap and only a VET that is medically qualified can do this procedure. 0.1cc of NDV flushed with saline fluid while the needle is inserted to ensure the NDV enters the spinal fluid.

I have posted the proceedure here under the topic Canine Distemper and under peer to peer section so you can print it and give it to your VET. The VET has to do this in the area of the cerebral magnum just below the bottom base of the skull which is where the spinal stem is located.

What you are seeing is the early stages of paralysis CAUSED by Canine Distemper breaching the blood brain barrier. So if you get your dog to the VET ASAP and get that NDV inside the spinal fluid you might have a chance to stop its progression in time before it gets worse and if you do >>>expect further progression because it takes time for the NDV to stop this progression. KEY IS THE EARLIER THE BETTER for results.

Do not give it any PARVO VACCINE OR ANY OTHER VACCINE for the other diseases. STOP.

Have your VET do the NDV-CSF tap procedure. You have to find Newcastles Disease Virus Vaccine. Such is found in poultry agricultural stores, and in some cases Universities. If they ask you why you want some, tell them you have chickens. Save yourself the trouble of having to explain your side and the reasons why. Understand.

The rest is up to you and this procedure is authentic medically. OK Nothing else is known to stop this progression except the serum which is different but cannot ship or transport via air. Sorry, so your best option is the NDV which is the primary one you need RIGHT NOW. All you need to buy is one vial and it comes with Saline. It is not expensive at all and quite cheap.

Once you get it keep it cold and then give it to YOUR VET to do the CSF tap. Do not attempt to do this procedure yourself, because you definitely will kill your animal, because you do not know how to do it manually. Your VET who is qualified in doing such CSF taps knows precisely what to do. Also tell him to give the dog some anti-shock meds to avoid problems before this NDV is given. Recovery from this operation is quite short about 1 hour tops.

Then take the dog home and pray and hope the disease progression stops fast enough. It varies in different breeds, and up to the dogs immune system response capability. Your dog will live, no doubt about it, so it might take 2 months before you will know how far the progression goes. It might be just one leg or two or all four etc., so the key is how fast your VET puts that NDV in that dog. Recovery of these symptoms vary time wise. In some cases not completely.

The serum (not Newcastles Vaccine) I know is quite good. Can get the dog to walk again in short time span. The recovery is phenominal and quite surprising.

So get on with this with your VET ASAP and find the Newcastles for your VET. Most VETS do not carry this vaccine. Understand.

This site is protected by their disclaimer, so understand this OK. The medical procedure so given here is from me Daveyo to give you hope and not involved with this site at all. OK. If you and your VET come to terms with your verbal agreement, then your OK. If not find some VET who will do this procedure. Do sign the waiver forms if they ask. At least you know the procedure and the vaccine is safe and authentic but I cannot vouch for the VET and his ability to do it right. OK. You have to be the judge on this yourself.

So let me know what happens and post it here. Hurry and good luck.

[maiziedog]

Found a vet to do the procedure. Although he'd never used it anywhere except for intraveinously, he agreed to administer to the vaccine around fluid of the spinal cord evidently on the lower back because that's where she's shaven. Re-reading your post, I see that it was supposed to be at the base of the brain stem. I'm hoping this will have the same effect. She's still got the chorea and is weak in the legs, but seems to be more alert and "with it" than earlier this morning. I'm certainly not expecting to have it be a miracle cure, but any glimmer of hope is reassuring. I guess it's just a wait and see game now. Any feedback you might want to give is welcome....

Thanks

[Daveyo]

NO>>>>> NOT IN THE BACK PART OR REAR!!!!!!. It has to be done in the Cerebrial Cranial Cavity the Foramen Magnum just below the skull where the cord stem is located. In the BACK AREA >> That is where fluids are flushed out from the CNS which returns back to the body.

Oh man now you can only hope. Why does not the VET follow the instructions as given??????. By putting it in the front under the skull, it also can get to the brain and cover the entire spinal cord top down to the tail where it is disposed of naturally. Geeeezzzzzzz.

You cannot do this again with NDV. This is a one time procedure. The only other hope you got is the serum and I cannot get it shipped out to you. Now maybe your VET can make this serum if this VET follows it straight as given and do not change it to suit their thinking and needs.

Then you can put this in the dog without a problem to the immune system.

Anti-Distemper Serum
1. The following protocol is for the production of anti-Distemper serum.(cytokines) NOT ANTIBODIES!
2. This serum is used S.Q. for the elimination of Distemper virus in acutely infected dogs in the body and stops the progression in the CNS.


Procedures for making serum
1. Dog- use a 10-12 month old mixed breed dog 60-100 lbs, young and healthy.
2. Do full lab work up to eliminate all possible health problems. Especially blood born diseases.
3. Dog MUST BE FULLY Vaccinated against all local diseases, at least 1 month prior.
4. DO NOT use breeds or individuals known to have immune deficiency problems.
5. Make up Newcastle virus vaccine 1000 dose vial. (Use only 6 cc of diluent. Discard balance.) La Sota strain. Other strains of this virus should work as well. This virus is your cell immunity inducer.
6. Place IV Catheter in dog.
7. Inject 2-3cc of Newcastle virus I.V. from your vaccine bottle. (. Treat dog with I.V fluids accordingly) (Do Not use Corticosteroids)
8. Induction of Newcastle’s disease virus for cellular immune serum (cytokines) may only be done once on any dog. The second time around only antibodies to Newcastle’s disease are produced. These are of no use.
9, Timing is essential for taking serum against distemper. Take blood 11-12 hours post injection (11-12 hrs post injection= Anti-viral factors=Very effective against Distemper Virus in VIVO.) Timing is EXTREMELY VERY IMPORTANT!!!!!. Interferon,antiviral,regulatory,anti-inflammatory cytokines all have different times of production.
10. All procedures must be sterile. 10.5-11 hours post injection anesthetize donor dog. Prepare dog at 10.5 hours before the following steps as instructed below beginning with step 11.
11. Place Jugular catheter.
12. Start I.V fluids.
13. Withdraw blood and inject into 10cc blood vials [sterile no additive vials] and allow the blood to clot. BETWEEN THE 11th and 12th hour.
14. Centrifuge immediately after clotting for clear serum. Do not allow RBC’s to lyse.
15. Remove serum and place into sterile bottles.
16. Place serum bottles in baggies and store in refrigerator. Bottles of serum can be stored for up to five years in a refrigerator.
17. Cryo-precipitates may form after refrigeration. Mixing causes clouding. This is not harmful.
18. May be filtered out with a .02micron filter. Keep sterile.
19. All my doner dogs have survived. I have not lost any.

Only your VET can do this so be advised. Once you have this serum, then it can be used on your dog and hopefully not too late.

This is the only option you got if you choose to go with it. Up to you. Your VET altered the instructions that I gave regarding the NDV to the CSF so I cannot be certain if it will work or not. If you do this with the serum and do exactly as given same for doing the NDV procedure then you might have a chance with the serum.

Again the disclaimer of this site is in effect. Make sure you understand this OK.

[maiziedog]

I am crushed to hear this. Is there any chance that it might help? I can't believe it. She's still showing no gum chewing, seizures, or anything really horrible neurologically, just the same amount of twitching and limb weakness. I am just sick about this.

[maiziedog]

I'm completely ignorant as to how the cerebral spinal fluid circulates. From what I can gather, in humans anyway it circulates down and back up the spinal cord back to the brain. Could you help me out in understanding it's route in dogs? I'm grasping here!

[Daveyo]

Yes there is still a chance doing the serum route. That is why I gave it to you here to give it to the VET and hopefully there is a dog somewhere that can create the serum for you. The vet has to follow the instructions completely and do it right and the timing is of most importance in getting that blood from the donor dog that is in excellent health and is fully vaccinated and has no parasite infections. Age of the donor animal is also important.

Oh gosh to explain the complexities here of how the CNS fluid works in humans and animals is tedious. It is of no consequences to you at the moment but trust me it has to flush out at the tail end the debris that the Brain and CNS has and makes (known as garbage). It has to get out somehow or you and me and the animals will get seizures and die from this garbage. The same principle of us humans and dogs that when we urinate or have bowel movement. It has to get out somewhere and somehow.

Understand??

Also in some cases when pressure builds up it has to get out somehow. I repeat in some cases. Most of the time surgery is the only means and alternative to relieve such pressure.

[Daveyo]

The description of the symptoms you have given is similar to Chorea, but what is happening is your dog is losing its myelin because the Distemper antibodies are present in the CNS thus triggering the dangerous T-4 killer cells which comes from the immune system in its efforts to eradicate the intruder, and in the process destroys the good cells which is the myelin and the schwann cells. Once the myelin gets damaged the axons in the nerve are exposed which is the electrical signals and it shorts out thus the dog begins to lose its coordination and gets paralysis. Twitching or involuntary movements of the muscles indicates the damage is happening at the cord stem. You do have the danger of seizures happening once the antibodies start reaching the brain. Dogs will expire in 14 days once seizures begin, and the seizures will intensify to the point of literally killing the dog. When the seizure starts it is sudden and without warning and the dog will go wild and try to climb a wall and bark like he got spooked, and then the lock up and the foaming begins. Just preparing you of what is to come in seizures and it gets really bad towards the end. Phenobarbital is a drug to slow down the seizures and its electical signals, but will not stop its progression. In regards to the paralysis, > As this continues it will eventually reach the lungs and heart and the dog also expires.

Both of these episodes and symptoms is progressive and the only two known methods has been given of which one is now shot to heck and the other is your last option to STOP THE PROGRESSION and remove this death sentence on your dog. If unable to do the last option I am sorry, and the dogs prognosis is FATAL.