[Sinaga]

2 weeks ago he lost his appettite, difficulty breathing and then his front left foot start twitching. We already take him to 4 different Vet.The 3rd vet diagnose him with a distemper by a blood test. She take care of the dog for 4 days but then he said it would be better to nurse him home. So we call another vet to give him the medication. The last vet still come to our house everyday to give him a shot of antibiotic and neurobion.

About 5 days ago the twitching on his left foot disappear but then he can't control his left foot. He keep bending his back every 5-10 second, seems like feeling a rush of pain, but not during deep sleep. And 2 days ago seizure start to happen, the first to the second seizure interval is about 24 hours. 2nd-3rd about 22 hours, 3rd-4th about 12 hours and so on. the last seizure he had was only 2 hours from the seizure before it.

There is no hardening of the pads, no chewing gum symptom. But now he totally lost his appetite and he can't even stand long enough to drink. He havent poo for 4 days now, and havent piss for 1 day (he still drink, i support him while he's drinking)

Is there any chance to save our puppy?

[Daveyo]

Right now your dog is having full blown ODE. To save your dog you need to do an emergency NDV-CSF tap immediately meaning right now.

I believe by the time you read this your dog probably will expire shortly. Your best hope right now is the lull or window that will occur and probably last perhaps maybe 48 to 72 hours. If you get this window do that tap immediately. The cure for both procedures takes 24 hours.

Here is the procedure since your time factor is very short. Give your dog the injection in the body of NDV first right now. You have to kill the virus in the body most importantly. At this same time, then prepare the dog for the emergency NDV-CSF tap and do this right after the body injection. If your fast enough and have a VET who is quick, there is a chance to save your dog provided your VET follows exactly as I have here for you. If that VET does anything else differently the VET will compromise the success severely. >

Body Injection:

In desperate circumstances, in the absence of available serum>> Newcastle’s Disease Virus vaccine (most common is the LaSorta Strain) can be injected either doing the IV method or directly into the blood vein using a needle and syringe into sick dogs. If they are not already severally immune compromised by the distemper virus they can respond and recover from distemper. The dose for this is 0.1cc of mixture per pound or 0.45kg, of which 1.0cc is for a 10 lb dog or 4.53kg. The formula given is based most importantly on the weight of the dog, so the heavier the dog the more NDV is needed. PLEASE NOTE THIS VACCINE CAN BE ONLY GIVEN ONE TIME ONLY TO THE DOG in the body. ANY ADDITIONAL NDV CAUSES ONLY ANTIBODIES THAT IT WAS DESIGNED FOR. AVOID ANY ADDITIONAL INJECTIONS. For those Vets concerned about themselves or staff, this virus vaccine has no deleterious effects on people. Use with sterile technique. Does not make the recipient animal ill.

Here is a table for those using either Pounds or Kg as weights:

0.1cc for every pound or 0.45kg

0.2cc for 2 pounds or 0.90kg

0.3cc for 3 pounds or 1.36kg

0.4cc for 4 pounds or 1.81kg

0.5cc for 5 pounds or 2.26kg

0.6cc for 6 pounds or 2.72kg

0.7cc for 7 pounds or 3.17kg

0.8cc for 8 pounds or 3.62kg

0.9cc for 9 pounds or 4.08kg

1.0cc for 10 pounds or 4.53kg

1.1cc for 11 pounds or 4.98kg

(add 0.1cc for every pound thereafter to 19 pounds or every 0.45kg)

2.0cc for 20 pounds or 9.07kg

3.0cc for 30 pounds or 13.60kg (and so on)

If between any of these weights always add another 0.1cc or go up to the next pound or next 0.45kg. NEVER SUBTRACT. For those using Kg weights you may round it out >ex 4.53kg can be 4.5kg to simplify the Dx.


NDV-CSF Injection

Newcastle’s Disease Virus ---is the inducer that will interfere with and stop the immune disorder causing neurologic damage in the canine. I have used the La Sorta strain only because it has been available. 1000 dose bottles with 6 cc of dilutent is your inducer. This material can be purchased at any agricultural store that deals with poultry.


INSTRUCTIONS FOR VET DOING A CSF TAP PROCEDURE TO INJECT THE NDV TO DOG - PLEASE SEE THE CHART BELOW.

THIS PROCEDURE HAS NOTHING TO DO WITH THE WEIGHT OF THE ANIMAL. IT HAS EVERYTHING TO DO WITH THE SIZE OF THE ANIMAL AT TIME OF CSF TAP PROCEDURE. THE WEIGHT FORMULA INVOLVES ONLY THE BODY INJECTION OF NDV.

Make sure you have the I.V. Fluids flowing, and give the dog ANTI-SHOCK MEDS to prevent phenolic shock, anesthetic to get the dog sleeping, a Cather and 2 needles plus 1 vial of NDV with the sterile solution and one empty sealable sterile vial.

Prepare animal by shaving the required area of the hair and sterilize the same area. Make sure the animal is definitely sleeping and does not move at all.

1. Place the needle in the Foramen Magnum (the large hole at the base of the skull where the spinal cord stem is located) (cerebral cranial cavity) . Please note being a VET you should know where this is.

2. Remove the required CNS fluid and LEAVE NEEDLE IN PLACE. This makes room for further injections. (SEE CHART BELOW)

3. Out of that required CNS fluid, discard some of this CNS fluid and or SAVE IT IN ANOTHER STERILE VIAL TO HAVE SUCH LAB TESTS DONE ON IT LATER ON TO CONFIRM SPECIFIC DISTEMPER ANTIBODIES at Antech Labs in USA, AND REFRIGERATE IMMEDIATELY.

4. Leave the remaining required CNS fluid in the needle syringe and then add the required amount of NDV (and a touch more to remove any air) into this same CNS fluid syringe and mix it together. Then inject the mixture of NDV and CNS fluid back to the animal via the needle hub previously in place.

5. SPECIAL NOTE: MAKE SURE THERE IS ABSOLUTELY NO AIR IN THE NEEDLE OR SYRINGE BEFORE INJECTING BACK THE NDV/CNS FLUID OR WHEN YOU FLUSH THE NEEDLE HUB WITH THE SALINE BACK INTO THE SPINAL CANAL .

6. Then flush THE NEEDLE HUB of 0.1cc of Saline (APPLIES TO ALL SIZES OF THE ANIMAL) so all the NDV goes into the spinal area and not be left in the hub of the needle. Then withdraw the needles out of the spinal area carefully and sterilize the puncture area to prevent infection at point of entry.

7. Some of this fluid will enter the Brain itself. No need to worry. THIS WILL NOT CAUSE A PROBLEM.

8. If the dog was not given the anti-shock meds prior to doing this procedure, phenolic shock will occur IMMEDIATELY after the injection. (It goes with a foreign substance (NDV virus inducer) being injected into the neural tissue. Expected but not a problem. TREAT FOR THE SHOCK IMMEDIATELY WITH SALINE.

HERE IS THE CSF TAP CHART FOR THE DOGS BASED ON THEIR SIZES: REMEMBER > SIZE AT TIME OF CSF TAP PROCEDURE So look at the size of the dog not the breed type unless it is fully grown, then you go based on the breed size.

Toy dogs get 0.1cc of NDV for CSF tap> take out 0.3cc fluid, leave 0.1cc in syringe, discard 0.2cc, then add 0.1cc NDV, mix and then inject, then plus 0.1cc saline to flush hub from another syringe by itself.

Small dogs get 0.2cc NDV for CSF tap > take out 0.5cc fluid leave 0.2cc in syringe, discard 0.3cc, then add 0.2cc NDV mix and then inject, then plus 0.1cc saline to flush hub from another syringe by itself.

Medium dogs get 0.3cc NDV for CSF tap> take out 0.7cc fluid leave 0.3cc in syringe, discard 0.4cc, add 0.3cc NDV, mix and then inject, then plus 0.1cc saline to flush hub from another syringe by itself.

Large dogs get 0.4cc NDV for CSF tap> take out 0.9cc fluid, leave 0.4cc in syringe, discard 0.5cc, then add 0.4cc NDV, mix and then inject, then plus 0.1cc saline to flush hub from another syringe by itself .

Giant dogs get 0.5cc of NDV for CSF tap> take out 1.1cc fluid, leave 0.5cc in syringe, discard 0.6cc, then add 0.5cc NDV, mix and then inject, then plus 0.1cc of saline to flush hub from another syringe by itself.

9. The dog will recover from the shock if treated properly and after the shock or after the procedure itself, Sterile the puncture at the Foramen Magnum, and you can remove the I.V Fluids after it wakes up, and let the dog rest and wait until it gets up on its own. Takes about an hour or a little less. Once the dog gets up it is safe for you to release it back to the owner and do give the following advisories to your client so they understand what to expect and what is involved.

9A. Do advise the owner the cure will take between 24-36 hours (average 24 hours) of which the NDV will stop the progression of the of the active C4 T-cells of further destruction, and it also will kill the Distemper Virus in the CNS and the dog will survive.

Hope this helps you. Make a copy of this and give to your VET immediately and tell him to hustle and do it and not debate. Your running out of time here.

Daveyo

[Sinaga]

I just got back from the vet, the vet is very2 interested with your method and he perform all the steps you give me. Now i just have to wait for Plato (our puppy) to recover. I'll keep you updated! Huge thanks!

[Sinaga]

Oh, and one other think. Two actually..

The vet seems to be interested with this treatment and maybe he wants to ask more question. I really wanted to give your contact, but i can't find it anywhere on this site. Can you give me a hint? A very simple one, i'm not good at guessing :D

And i live in Bali, Indonesia. So i don't know if the virus is different here than the one in the States. Do you think that it will be a problem? Like i said, Plato don't have the hard pad and the chewing gum symptom, he just go straight to muscle twitching and the next week after the twitching lost, a seizure start to happen.

[Daveyo]

As of the Virus of distemper there are different strains of this disease, however they all fall under the same tree line. The strains do affect the dogs in different ways. There is a strain that affects dogs for seizures and another different strain that affects dogs for paralysis.

Example. Skippy here had a reading of 1/50 distemper antibodies in the CNS
Charlie here had a reading of 1/100 distemer antibodies in the CNS

The above means that Skippy had less Distemper antibodies than Charlie but it was Skippy who took on the most damage to the Brain area. Skippy has the seizures and Charlie had the Paralysis.

So the strength of the strain plays a role here yet it is Distemper Virus. If you want to find out more about this disease do go to [moderator note: website address has been removed] and you can read up on the material there after you register in.

In the meantime keep me posted.

Daveyo

[Sinaga]

Just got back from the vet.

How can i tell wether the vet is doing the CSF tap succesfuly or not? Because it was his first time.

It's been 24 hours and now Plato haven't move a lot, only sleeping. When he saw me he just trying to reach me with his front leg, but didn't trying to get up. I put my hand on his mouth and he gave me a very light bite. His neck moving, but very2 little. The vet put him on another IV this morning.

Before the tap, as i told you we give Plato antibiotic and neurobion (like a vitamin for the nerve). Do you think we should stop it or keep on giving him the vitamin for another several days?

In Indonesia, it's very2 hard to find a vaccine with killed virus, can you give me an advice on how to get one?

I registered at your forum last night. I print everything i can find about distemper and gave it to the vet. I hope it can be usefull for him.

[Daveyo]

Oh boy, you mean to tell me this VET never did a CSF tap before???

The odds are slim now. The dog should have gotten up and been fine after that tap had the VET done it correctly. If that needle went in too far this is usually the result because it touched that cord.

By now if the NDV was inserted correctly and done properly, the virus is dead in the CSF and Brain area. If done wrong you cannot give another NDV injection. It is only a one shot deal.

Another VET tried this method in the Philippines and it was a failure and they had to expire the dog.

You have to understand your only talking about a 1/16th in clearance between the cord and the spinal stem wall. Not to mention the vertebrae being in the way and you have to know exactly how to insert it to the foramen Magnum (cerebral cranial cavity) of which is where the brain connections and the spinal connections are located. This area is very easy to mess up and all if that needle so much as touches those vital parts.

When VETS are trained to do spinal taps my friend it takes them on average of 10 tries before they get the right depth and another 10 more before they get the handle on it to do it comfortably without damaging the cord stem on the animals. When they train they do it on live animals and most are put to sleep permanently after they are allowed to wake up to see the immediate results of the tap test. When they do it right the animal will get up and be normal. If wrong they never get up and usually also die as well.

So with this in mind, you figure out the odds on your beloved pet.

What antibiotics were you giving the animal before the tap?? When mine was done there was no antibiotic and no vitamins given either. The instructions were followed precisely and I did not alter one step from the procedure.

I gave that warning before, about that VETS will attempt to change the medical protocol. Why they never follow it precisely is beyond me. The next thing I hear they blame the medical protocol as given and recorded here is not any good. Of course they need to blame but they really should be blaming themselves for not following instructions as given. So who's fault is this????

Your going to have to watch your dog very carefully. Especially the nerve checking. Take a sewing needle and tap the skin at various places around the body starting from the middle of the back down to the legs. If the animal reacts to the slightest pressure from that sewing needle then that is good. If you push down and put pressure on the skin and no reaction from the animal that means a dead zone and no nerve feeling.

Let me know what you come up with on that test yourself.

Daveyo

[Sinaga]

About the antibiotic and the vitamin, he takes it a day before the procedure. I've told you in my first post. About the antibiotic and the neurobion. It was before i post anything in this website.

About the CSF, we don't have any other choice, he's the only one who's willing to do it. But before the CSF, my puppy condition was very bad. He don't even walk. If the CSF given in that condition, will the dog stand on his foot right after he wakes from the CSF?

I will do the test with the needle tommorow. But earlier today when i was visiting him, he give a respon to the touch on his mouth. And when i touch his tongue, he give me a light bite. Is that a good sign?

[Daveyo]

Oh your dog was completely paralyzed??????

Ok now I understand. Hmmmm, ok

The NDV now has killed the virus in the CNS. What is the status in the body? Did you give the dog any NDV in the body yet?? It has to be done at both places to kill off the virus permanently.

How is the breathing??? Any signs of pneumonia present????? Have the VET check the lungs OK Very important here.

Do not give the dog any bath for now. Stay away from water. Minimum 3 weeks

Here is what is going to happen

Your dog will not show signs of recovery right away at all. You have to wait minimum of 30 days until this damage bottoms out that was caused by the virus. So please watch the breathing and make sure it is by your side all the time, to help it pee and to poo, to give it water and to help it eat. This is going to be a 24/7 deal for you for a few months.

After 30 days there will be a lull period probably taking a good 2-3 weeks. Hopefully by week 7-8 the dog will begin to show you signs of being bothered a lot.

The dog will be moaning to you a lot acting very bothered. This is your first sign and the beginning of the recovery period. Mark it down on the calendar OK.

Let the dog ride it out. It might last perhaps 3 days or less give or take. Then nothing happens. About near 2 weeks another excitation takes place and again 2-3 days being bothered and moaning.

You do the sewing needle test after 30 days from that tap. You need to know precisely where all the dead zones are located on your dog, and what areas are active at that time. Mark all this down.

From the first nerve excitation to 30 days later then do a needle test check. Compare to your last notes to see if any improvement is noted. There should be some.

Be patient and wait and allow the dog to recover on its own. If all goes well, I would expect your dog to begin to show good signs about 90 days later from the first excitation to want to crawl around. If this happen your on the right track.

If on the right track give or take so don't panic there is a good chance your dog will begin to stand up on its own with a bit of help about 4 months from the CSF tap. About 5 months it will stand up on its own and walk around with shaky coordination etc. About 6 months walking around much better and stronger coordination and about 7 months really walking around and moving around fast on its own.

If I guess right give or take your looking between 7-9 months. It is estimated that this recovery should last about a good year. After that I do believe it will peak itself and there will be no further recovery.

I have a paralysis chart on my site. Copy it and print it out. You can gauge your dog on its recovery factors on the percentage scale. Your target is 60- 65% If that dog goes higher it is a true blessing.

Right now mine is at 75% closer to 80%. I don't expect much more if any maybe up to 85% tops. For me I am satisfied with my dogs recovery. Getting him to run and go up and down the stairs is going to be a real miracle indeed.

If that tap again pray and hope OK, was done right, you just cancelled out the ODE death sentence, stopped the virus completely both in the body and CSF and if all true, give that dog time to recover.

Its immune system just received an insult caused by the distemper virus and believe me its as nasty as it comes short of Rabies. The NDV stopped most importantly the C4 T-cells from destroying any more Myelin and Schwann cells. Basically it turned off that switch. Those C4 T- cells was the other factor that causes the full ODE effect. Turning it off, cancelled it out.

What I mean by turning it off I mean by it being brought under control again normally. The virus caused it to go haywire and it was attacking its own good cells nothwithstanding the fact the virus also was there too. The cytokine storm created by the NDV wiped out that virus and took over the control of the C4-T cells and reverted it back to normal state.

You can bring your dog home but make sure you give NDV to the body and take care of the pneumonia. Pneumonia always accompanies Distemper.

Once home good nursing care from you does it all for the dog. It will respond for you.

After about a week do take some blood and have it check for full blood count. You need to know where the WBC is at. If too low get Nupogen. You should be able to find that at a major hospital. They usually stock on it. The max you will need is 0.3cc tops. No more than that. It is very powerful and just 0.1cc of it shoots up the WBC quite a lot. WBC is the dogs main immune response defense against bacteria and viruses. OK. Your target is 17.0 and that is very good defense. I do have a blood count chart on my site and it is quite informative.

If your dog survives that CSF needle of which you will know in about 3 days from now, I have to congratulate that VET. Very few doctors ever get it right the first time and the dog escapes cord damage. Meaning your dog was one of the lucky 5 % that did not receive cord damage caused by a needle attemped by a VET the first time. The incredible odds were against the VET 95% of which the first attempt will not succeed.

Keep posting and let me know whats going on

Daveyo

[Sinaga]

Will do! I'll post something here as soon as i notice anything! Thanks!